{"id":42210,"date":"2024-02-13T14:56:35","date_gmt":"2024-02-13T13:56:35","guid":{"rendered":"https:\/\/mag.bynez.com\/?p=42210"},"modified":"2024-02-23T17:14:10","modified_gmt":"2024-02-23T16:14:10","slug":"nez-x-gdr-o3-smelling-of-roses","status":"publish","type":"post","link":"https:\/\/mag.bynez.com\/en\/nez-x-gdr-o3-en\/nez-x-gdr-o3-smelling-of-roses\/","title":{"rendered":"Nez x GDR O3 \u2013 Smelling of roses"},"content":{"rendered":"    <div id=\"chapo-block_a5eed4fbaf138a81a75c53e93888ea55\" class=\"chapo\">\r\n        <blockquote class=\"chapo-blockquote\">\r\n            <span class=\"chapo-text\"><p>We recently announced the launch of <a href=\"https:\/\/mag.bynez.com\/en\/nez-x-gdr-o3-en\/nathalie-mandairon-various-unique-projects-have-been-launched-thanks-to-gdr-o3\/\">a partnership between GDR O3 and Nez<\/a>. It gives us the perfect opportunity to offer you a regular round-up of the studies resulting from the work undertaken by the research group and its team of scientists from every field with a common focus: odour in all its forms.<br \/>\nThe idea? Nez reads the scientific publications, and offers you a simpler, more accessible version.<br \/>\n For example, did you know that a better understanding of the origin of the rose\u2019s fragrance would pave the way for innovations both in cosmetics and pharmacy? This is, among other things, what the CNRS research engineer and member of the GDR O3 Beno\u00eet Boachon explained to us.<\/p>\n<\/span>\r\n        <\/blockquote>\r\n        <style type=\"text\/css\">\r\n            #chapo-block_a5eed4fbaf138a81a75c53e93888ea55 {\r\n                background: ;\r\n                color: ;\r\n            }\r\n        <\/style>\r\n    <\/div>\r\n    \n\n\n<p>There is one odour everyone finds it easy to detect and everyone enjoys: the smell of the rose, the undisputed queen of flowers. But, until recently, we had no idea about the origin of its captivating scent. Sylvie Baudino, head of the CNRS laboratory for plant biotechnologies applied to aromatic and medicinal plants (LBVpam) at Universit\u00e9 Jean Monnet, led an initial study published in 2015 in <em>Science<\/em> magazine that made it possible to identify a key enzyme \u2013 NUDX1 hydrolase \u2013 involved in the synthesis of geraniol and other terpenes that help to create the rose\u2019s olfactory signature. We talked about the study in the <a href=\"https:\/\/shop.bynez.com\/boutique\/nez-the-olfactory-magazine\/nez-the-olfactory-magazine-07-the-animal-sense\/\" target=\"_blank\" rel=\"noreferrer noopener\"><em>Nez#07 \u2013 The Animal<\/em> <em>Sense<\/em><\/a> Odorama.<\/p>\n\n\n\n<p>More recently, research by Beno\u00eet Boachon of LBVpam, as part of Corentin Conart&#8217;s thesis directed by Jean-Claude Caissard, has revealed the upstream enzyme for NUDX1 hydrolase that provides its substrate. They have studied its evolution in order to understand how it acquired the role of producing the precursor to these scented molecules, a phenomenon unique to the rose.&nbsp;<\/p>\n\n\n\n<p>Unlike most plants, the geranyl diphosphate (GDP) involved in the synthesis of geraniol is not produced in the chloroplasts by the enzyme known as GPP synthase in rose flowers, but by an enzyme present in the cytosol, the liquid part of the cells. This bifunctional enzyme, called GFPP synthase 1 (G\/FPPS1), actually produces both GPP and farnesyl diphosphate (FDP), another essential precursor in the synthesis of terpenoids such as sesquiterpenes and plant sterols. The study, <a href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2221440120\">published in the <em>Proceedings of the National Academy of Sciences of the United States of America<\/em><\/a><em> (PNAS)<\/em>, also highlights the fact that the bifunctional G\/FPPS1&nbsp; is present in all members of the Rosaceae family.<\/p>\n\n\n\n<p>While these results might appear of little interest to non-specialists, Beno\u00eet Boachon explains that \u201cthis discovery improves our understanding of how certain plants produce scents via an alternate metabolic pathway, opening the way to a re-examination of the generally accepted belief about plants; it may also have implications for the perfumery, cosmetics and pharmaceutical industries.\u201d<em>&nbsp;<\/em>This is because \u201csynthetic biology and metabolic engineering are increasingly used to produce targeted molecules from plants, sometimes rare ones, using yeast, for example, without organic synthesis.<em> <\/em>The discovery of this previously unknown biosynthesis pathway could, therefore, be used to produce perfumes more efficiently from yeast.<em> <\/em>Geraniol is also a precursor for certain anti-cancer molecules, such as vinblastine, produced by harvesting Madagascar periwinkle.<em> <\/em>This discovery will also help improve understanding of how aromas from terpenes are produced in the fruits of the Rosaceae species.\u201d<\/p>\n\n\n\n<p>We don\u2019t know what you think, but we feel the outlook has never been rosier!<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Contact: <a href=\"mailto:benoit.boachon@univ-st-etienne.fr\">benoit.boachon@univ-st-etienne.fr<\/a><\/li>\n\n\n\n<li>More about GDR O3 on its website: <a href=\"https:\/\/www.gdr-o3.cnrs.fr\">www.gdr-o3.cnrs.fr<\/a><\/li>\n<\/ul>\n\n\n\n<p><em>Main visual: \u00a9 Ad\u00e8le Ch\u00e9vara<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Did you know that a better understanding of the origin of the rose\u2019s fragrance would pave the way for innovations both in cosmetics and pharmacy? This is, among other things, what the CNRS research engineer and member of the GDR O3 Beno\u00eet Boachon explained to us.<\/p>\n","protected":false},"author":12139,"featured_media":42208,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"pmpro_default_level":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"mc4wp_mailchimp_campaign":[],"footnotes":""},"categories":[677,7500,1415,1416,1418],"tags":[7559,7414,7561,931,3291,3389,986,5960,823,7412],"series":[],"ppma_author":[2930],"class_list":["post-42210","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-nez-x-gdr-o3-en","category-olfactory-culture","category-perfume","category-science-en","tag-benoit-boachon-en","tag-cnrs-en","tag-corentin-conart-en","tag-natural-raw-materials","tag-perfumes-en","tag-rose-en","tag-sense-of-smell","tag-non-classifiee-en-12","tag-smells","tag-sylvie-baudino-en","pmpro-has-access"],"pp_statuses_selecting_workflow":false,"pp_workflow_action":"current","pp_status_selection":"publish","pp_post_mime_type":"","acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nez x GDR O3 \u2013 Smelling of roses - Nez the olfactory cultural movement<\/title>\n<meta name=\"description\" content=\"Did you know that a better understanding of the origin of the rose\u2019s fragrance would pave the way for innovations both in cosmetics and pharmacy? 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This is, among other things, what the CNRS research engineer and member of the GDR O3 Beno\u00eet Boachon explained to us.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/mag.bynez.com\/en\/nez-x-gdr-o3-en\/nez-x-gdr-o3-smelling-of-roses\/\" \/>\n<meta property=\"og:site_name\" content=\"Nez\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/nezlarevue\" \/>\n<meta property=\"article:published_time\" content=\"2024-02-13T13:56:35+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-02-23T16:14:10+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/mag.bynez.com\/wp-content\/uploads\/2024\/02\/GDRO3_6.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"630\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Jessica Mignot\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica Mignot\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/mag.bynez.com\\\/en\\\/nez-x-gdr-o3-en\\\/nez-x-gdr-o3-smelling-of-roses\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/mag.bynez.com\\\/en\\\/nez-x-gdr-o3-en\\\/nez-x-gdr-o3-smelling-of-roses\\\/\"},\"author\":{\"name\":\"Jessica Mignot\",\"@id\":\"https:\\\/\\\/mag.bynez.com\\\/en\\\/#\\\/schema\\\/person\\\/ef364b8b10fd203d1e5e2734de313584\"},\"headline\":\"Nez x GDR O3 \u2013 Smelling of roses\",\"datePublished\":\"2024-02-13T13:56:35+00:00\",\"dateModified\":\"2024-02-23T16:14:10+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/mag.bynez.com\\\/en\\\/nez-x-gdr-o3-en\\\/nez-x-gdr-o3-smelling-of-roses\\\/\"},\"wordCount\":466,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/mag.bynez.com\\\/en\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/mag.bynez.com\\\/en\\\/nez-x-gdr-o3-en\\\/nez-x-gdr-o3-smelling-of-roses\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/mag.bynez.com\\\/wp-content\\\/uploads\\\/2024\\\/02\\\/GDRO3_6.jpg\",\"keywords\":[\"Beno\u00eet Boachon\",\"CNRS\",\"Corentin Conart\",\"Natural raw materials\",\"Perfumes\",\"Rose\",\"Sense of smell\",\"Smell\",\"Smells\",\"Sylvie Baudino\"],\"articleSection\":[\"News\",\"Nez x GDR O3\",\"Olfactory Culture\",\"Perfume\",\"Science\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/mag.bynez.com\\\/en\\\/nez-x-gdr-o3-en\\\/nez-x-gdr-o3-smelling-of-roses\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/mag.bynez.com\\\/en\\\/nez-x-gdr-o3-en\\\/nez-x-gdr-o3-smelling-of-roses\\\/\",\"url\":\"https:\\\/\\\/mag.bynez.com\\\/en\\\/nez-x-gdr-o3-en\\\/nez-x-gdr-o3-smelling-of-roses\\\/\",\"name\":\"Nez x GDR O3 \u2013 Smelling of roses - Nez the olfactory cultural movement\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/mag.bynez.com\\\/en\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/mag.bynez.com\\\/en\\\/nez-x-gdr-o3-en\\\/nez-x-gdr-o3-smelling-of-roses\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/mag.bynez.com\\\/en\\\/nez-x-gdr-o3-en\\\/nez-x-gdr-o3-smelling-of-roses\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/mag.bynez.com\\\/wp-content\\\/uploads\\\/2024\\\/02\\\/GDRO3_6.jpg\",\"datePublished\":\"2024-02-13T13:56:35+00:00\",\"dateModified\":\"2024-02-23T16:14:10+00:00\",\"description\":\"Did you know that a better understanding of the origin of the rose\u2019s fragrance would pave the way for innovations both in cosmetics and pharmacy? 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